Reference of 77513-58-7, Chemistry is the experimental science by definition. We want to make observations to prove hypothesis. For this purpose, we perform experiments in the lab. 77513-58-7, Name is Ethyl 2-oxotetrahydrofuran-3-carboxylate,introducing its new discovery.
Bis(trimethylsilyl) Sulfate Catalysis in gamma-Lactonization of Cyclopropanecarboxylates Activated by Carbonyl Substituents on alpha-Carbon
The title reaction of 1-carbonyl substituted cyclopropanecarboxylates proceeds under C(1)-C(2) bond cleavage to produce gamma-lactones.Stereochemically, the reaction takes two pathways: (1) substrates with a cationstabilizing group like vinyl on C(2) give thermodynamically favored gamma-lactones having the thermodynamically more stable arrangement of substituents irrespective of the configuration of the cyclopropane substrates, (2) substrates without such a cation-stabilizing group afford gamma-lactones under ca. 70percent inversion at C(2) reaction center.
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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem