Related Products of 52449-98-6, Because a catalyst decreases the height of the energy barrier, its presence increases the reaction rates of both the forward and the reverse reactions by the same amount.52449-98-6, Name is Oxolane-2-carbonyl chloride, molecular formula is C5H7ClO2. In a article£¬once mentioned of 52449-98-6
New insights into the torquoselectivity of the staudinger reaction
To understand the torquoselectivity and the electronic effects of the Staudinger reaction, a study using a combination of experiments and DFT calculations has been conducted for the reactions of an unsymmetric cyclicketene and cyclic imines with different electronic properties. The pred ominant formation of the donor-in beta-lactams, the torquoelectronically disfavored products, was observed for the first time. The Hammett analyses reveal a close relationship between the donor-out/donor-in productratio and the electronic nature of the imines. The kinetic competition experiments and DFT calculations indicate that the two-step Staudinger r eaction shows different rate-determining steps in the donor-in and donor-out pathways. Our investigations reveal that the torquoelectronic control in the Staudinger reaction is quite different from that in the ring-opening reaction of cyclobutene derivatives. The diastereoselectivity of the Staudinger reaction involving an unsymmetric disubstituted ketene cannot be simply rationalized or predicted by the torquoelectronic model.
A reaction mechanism is the microscopic path by which reactants are transformed into products. Each step is an elementary reaction. In my other articles, you can also check out more blogs about 52449-98-6
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Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem