One of the major reasons for studying chemical kinetics is to use measurements of the macroscopic properties of a system, Computed Properties of C6H8O3, such as the rate of change in the concentration of reactants or products with time.In a article, mentioned the application of 17347-61-4, Name is 2,2-Dimethylsuccinicanhydride, molecular formula is C6H8O3
Novel inhibitors of 17beta-hydroxysteroid dehydrogenase type 1: Templates for design
The 17beta-hydroxysteroid dehydrogenases (17beta-HSDs) catalyze the interconversion between the oxidized and reduced forms of androgens and estrogens at the 17 position. The 17beta-HSD type 1 enzyme (17beta-HSD1) catalyzes the reduction of estrone (E1) to estradiol and is expressed in malignant breast cells. Inhibitors of this enzyme thus have potential as treatments for hormone dependent breast cancer. Syntheses and biological evaluation of novel non-steroidal inhibitors designed to mimic the E1 template are reported using information from potent steroidal inhibitors. Of the templates investigated biphenyl ethanone was promising and led to inhibitors with IC50 values in the low micromolar range.
One of the oldest and most widely used commercial enzyme inhibitors is aspirin, Computed Properties of C6H8O3, which selectively inhibits one of the enzymes involved in the synthesis of molecules that trigger inflammation. you can also check out more blogs about 17347-61-4
Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem