New explortion of ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 149809-43-8, and how the biochemistry of the body works.category: Tetrahydrofurans

In homogeneous catalysis, the catalyst is in the same phase as the reactant. The number of collisions between reactants and catalyst is at a maximum.In a patent, 149809-43-8, name is ((3R,5R)-5-((1H-1,2,4-Triazol-1-yl)methyl)-5-(2,4-difluorophenyl)tetrahydrofuran-3-yl)methyl 4-methylbenzenesulfonate, introducing its new discovery. category: Tetrahydrofurans

Method for preparing high-purity posaconazole (by machine translation)

The invention discloses a method for preparation of posaconazole, first of all, BP004b04 with oxalic acid to form the salt, to obtain the POE; secondly, POE with di-tert-butyl b carbon ester in the presence of an alkali reaction to obtain POP, POP recrystallization; once again, with the POK POP in the presence of an alkali reaction to obtain the POR, POR removes uncle butyl carbonate protecting group, to obtain POS; finally POS POB ring obtained, with the POB POA reaction posaconazole. The method of the invention, obtained in the posaconazole, the diastereoisomeric isomer content ? 0.01%, and the whole route total yield is high. (by machine translation)

We¡¯ll also look at important developments in the pharmaceutical industry because understanding organic chemistry is important in understanding health, medicine, the role of 149809-43-8, and how the biochemistry of the body works.category: Tetrahydrofurans

Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem