17347-61-4, Chemistry can be defined as the study of matter and the changes it undergoes. You¡¯ll sometimes hear it called the central science because it is the connection between physics and all the other sciences, starting with biology.17347-61-4, Name is 2,2-Dimethylsuccinicanhydride, molecular formula is C6H8O3, introducing its new discovery.
Synthesis and in vitro antitumor activities of lupeol dicarboxylic acid monoester derivatives
Ten lupeol dicarboxylic acid monoester derivatives as new potent antitumor agents were synthesized and evaluated for in vitro antitumor activities against A549, LAC, HepG2 and HeLa cell lines. Among them, compounds 1-5 showed excellent antitumor activities against all tested tumor cell lines and compounds 6-10 exhibited high activities against A549, HepG2 and HeLa cells, exceeded lupeol, lupanol and doxorubicin. Compound 2 displayed the highest potent antitumor activities with IC50 values of 5.78 muM against A549 cell, 2.38 muM against LAC cell, 6.14 muM against HepG2 cell and 0.00842 muM against HeLa cell.
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Reference£º
Tetrahydrofuran – Wikipedia,
Tetrahydrofuran | (CH2)3CH2O – PubChem