17347-61-4, 2,2-Dimethylsuccinicanhydride is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Example 154-[4-(2-tert-Butylphenyl)piperazin-1-yl]-2,2-dimethyl-4-oxobutanoic acidA mixture of 1-(2-tert-butylphenyl)piperazine dihydrochloride obtained in Reference Example 1 (400 mg), 2,2-dimethylsuccinic anhydride (400 mg), triethylamine (1.39 mL), and tetrahydrofuran (20 mL) was stirred at room temperature for over-night.Water was added to the reaction solution, and the mixture was extracted with ethyl acetate.The ethyl acetate layer was washed with saturated brine, and dried over anhydrous magnesium sulfate.The solvent was evaporated under reduced pressure to provide the title compound (1.03 g, 95percent) as a colorless solid.1H NMR (300 MHz, DMSO-d6) delta 1.17 (s, 3H), 1.19 (s, 3H), 1.41 (s, 9H), 2.54-2.84 (m, 7H), 3.06-3.23 (m, 1H), 3.90-3.95 (m, 1H), 4.38-4.40 (m, 1H), 7.11-7.16 (m, 1H), 7.19-7.24 (m, 1H), 7.30-7.36 (m, 2H), 11.79 (br, 1H)., 17347-61-4
As the paragraph descriping shows that 17347-61-4 is playing an increasingly important role.
Reference£º
Patent; Kasai, Shizuo; McGee, JR., Kevin Francis; US2012/71489; (2012); A1;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem