With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.16874-33-2,Tetrahydrofuran-2-carboxylic acid,as a common compound, the synthetic route is as follows.
a) Preparation of Acid Chloride7.8 gms of tetrahydrofuroic acid and 50 ml toluene were charged in a dry flask under nitrogen. 8.7 gms of thionyl chloride were added dropwise at 25-30 C. The reaction mass was stirred for 1 hour., 16874-33-2
The synthetic route of 16874-33-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; CIPLA LIMITED; US2010/256370; (2010); A1;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem