219823-47-9, (R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
4-(beta-D-glucopyranos-1-yl)-1-methyl-2-f4-(^SJ-tetrahvdrofuran-3-yloxy)-benzvn- benzene (R)-3-(4-methyIphenylsulfonyloxy)-tetrahydrofuran (4.9 g) is added to a mixture of 4- (beta-D-glucopyranos-1-yl)-2-(4-hydroxy-be?zyl)-1 -methyl-benzene (4.9 g) and cesium carbonate (6.6 g) in dimethylformamide (50 mL). The mixture is stirred at 60 0C for 8 h, before more cesium carbonate (0.7 g) and (R)-3-(4-methylphenyi-suIfonyIoxy)- tetrahydrofuran (0.5 g) are added. After an additional 14 h stirring at 80 0C, the mixture is cooled to ambient temperature, diluted with ethyl acetate and washed with brine. The organic phase is dried (sodium sulphate) and the solvent is removed. The residue is purified by chromatography on silica gel (dichloromethane/methanol 1 :0 -> 4:1). Yield: 2.68 g (46% of theory) Mass spectrum (ESI+): m/z = 448 [IvRNH4] +, 219823-47-9
219823-47-9 (R)-Tetrahydrofuran-3-yl 4-methylbenzenesulfonate 13837325, aTetrahydrofurans compound, is more and more widely used in various fields.
Reference£º
Patent; BOEHRINGER INGELHEIM INTERNATIONAL GMBH; BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG; WO2008/49923; (2008); A1;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem