17347-61-4, 2,2-Dimethylsuccinicanhydride is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Step A: Intermediate II A solution of 3,3-dimethyl-dihydrofuran-2,5-dione I (25 g, 195 mmol) in anhydrous EtOH ( 150 mL) was stirred at 50 ¡ãC overnight. After cooling down to room temperature, the solvent was removed under reduced pressure with a rotary evaporator and the residue was triturated with hexane at -50 ¡ãC to afford the intermediate II (25 g, 33 mmol, 67.9 percent) as a white solid. 1 H NMR (400 MHz, CDCI3) 5 ppm 4.13-4.18 (2H, q, J = 7.2 Hz), 2.62 (2H, s),1.28 (6H, s), 1.32-1 .25 (3H, t, J = 7.6 Hz). LC/MS: m/z calculated 174.1 , found 1 3.1 (M-1 )-., 17347-61-4
The synthetic route of 17347-61-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; GLAXOSMITHKLINE LLC; GAO, Daxin; HAN, Nianhe; JOHNS, Brian; JIN, Zhimin; NING, Fangxian; TANG, Jun; WU, Yongyong; YANG, Heping; WO2013/20245; (2013); A1;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem