4100-80-5, 3-Methyldihydrofuran-2,5-dione is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated,4100-80-5
EXAMPLE A284-(4-acetylaminophenyl)-2-methyl-4-oxobutanoic acid22 ml (0.28 mol) of dimethylformamide were added dropwise to 133.34 g (1.0 mol) of finely powdered aluminium chloride within 20 minutes, while cooling externally with ice. After the strongly exothermic reaction died down, 13.517 g (0.1 mol) of acetanilide and 11.413 g (0.1 mol) of methylsuccinic acid anhydride were added all at once and at an initial temperature of 60¡ã C., during which time the mixture heated up to about 80¡ã C. It was kept for another 3 hours at a temperature of 60-70¡ã C., the still hot mixture was stirred into 1 kg of crushed ice, 60 ml, of conc. hydrochloric acid were added and the mixture was left to stand overnight at ambient temperature. The precipitate formed was suction filtered and thoroughly washed with water. It was taken up in 150 ml of methanol, stirred for 30 minutes at 50¡ã C., then for another 30 minutes while cooling externally with ice and the precipitate was suction filtered. After drying in a circulating air dryer at 60¡ã C., 10.4 g (42percent of theoretical) of colourless crystals were obtained, m.p. 229-231¡ã C. and Rf 0.48 (El I).IR (KBr): 1714.6, 1662.5 cm-1 (CO)
As the paragraph descriping shows that 4100-80-5 is playing an increasingly important role.
Reference£º
Patent; Boehringer Ingelheim Pharma GmbH & Co. KG; US7230001; (2007); B1;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem