The synthetic route of 17347-61-4 has been constantly updated, and we look forward to future research findings.
17347-61-4, 2,2-Dimethylsuccinicanhydride is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
a) 2,2-Dimethyl-4-oxo-4-piperidin-l-yl-butyric acid; To solution of 2,2-dimethylsuccinic anhydride (1.0 g, 7.8 mmol) and triethylamine (0.79 g, 078 mmol) in CH2Cl2 (40 mL) was slowly added a solution of piperidine (0.66 g, 7.8 mmol) in CH2Cl2 (10 mL) at RT. The mixture was stirred for 4 hrs. NaOH 1.0M solution was added and the aqueous layer collected and subsequently acidified to pH 4 using HCl 2.0 M solution. Extraction with CHCI3 and evaporation of the solvent gave a crude product clean enough to be used without further purification.1.63 g; 98percentC11H19NO3 calculated 213; found M+ 214/M- 212Lc Rt (5 min)= 1.56 NMR (400 MHz, dmso-d6): 1.10 (6H, s); 1.32-1.37 (2H, m); 1.40- 1.44(2H, m); 1.50- 1.55 (2H, m); 2.50 (2H, s); 3.31-3.35 (4H, m); 11.7 (IH, br s)., 17347-61-4
The synthetic route of 17347-61-4 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; SIENA BIOTECH S.P.A.; WYETH PHARMACEUTICALS; WO2007/98826; (2007); A2;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem