Analyzing the synthesis route of 17347-61-4

17347-61-4, As the paragraph descriping shows that 17347-61-4 is playing an increasingly important role.

17347-61-4, 2,2-Dimethylsuccinicanhydride is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

The compound 6 (349 mg, 0.5 mmol) is dissolved in anhydrous pyridine (8 ml) in, adding 2, 2 – dimethyl succinic anhydride (320 mg, 2.5 mmol), DMAP (61 mg, 0.5 mmol), after dissolving completely, microwave reactor is heated to 160 ¡ãC, reaction 3 h. The end of the reaction, by adding ethyl acetate (50 ml), for 10percent HCl to adjust the pH 4 – 5; organic layer is saturated salt water washing (25 ml ¡Á 3), dried with anhydrous sodium sulfate, filtered, concentrated under reduced pressure to remove the solvent, silica gel column chromatography (hexane: ethyl acetate=1:1), to obtain white solid 302 g, is compound 9, yield 73percent.

17347-61-4, As the paragraph descriping shows that 17347-61-4 is playing an increasingly important role.

Reference£º
Patent; Chen Zhong; Duan Huaqing; Yang Shilin; Li Guoxiong; (26 pag.)CN109485688; (2019); A;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem