63095-51-2,63095-51-2, (R)-4-Propyldihydrofuran-2(3H)-one is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Add phenol (18.8g, 200.0mmol) and tetraisopropyl titanate (2.8g, 10.0mmol) to a 500ml three-necked bottle with stirring function, aan additional 250 ml of toluene was added and the mixture was stirred at reflux for 1 h. The solvent was evaporated under reduced pressure. Toluene (200 ml) and compound (R)-4-propyldihydrofuran-2-one (12.8 g, 10.0 mmol) were added to the reaction system, and the reaction was refluxed for 36 h. Reduce the reaction system to room temperature, add 2M dilute hydrochloric acid to adjust the pH to 5-6, the layers were separated and the organic phase was washed with water. Rotary evaporation to remove toluene, purification by column chromatography gave the compound (R)-3-hydroxymethylhexanoic acid phenyl ester.
As the paragraph descriping shows that 63095-51-2 is playing an increasingly important role.
Reference£º
Patent; Fujian Haixi New Drug Initiative Co., Ltd.; Kang Xinshan; Wang Ruyong; Ye Yizhang; Gong Xuan; Zhang Fengsen; Wang Zhonghong; Li Dandan; Fu Yueli; Feng Yan; (35 pag.)CN110357790; (2019); A;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem