63095-51-2, (R)-4-Propyldihydrofuran-2(3H)-one is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
Under nitrogen protection,willBuvacizine Intermediate III(128.1 g, 1 mol) was dissolved in 1 L of dichloromethane,Cooling to 0 ,Was added trimethylsilyl iodide (150mL),The reaction solution was stirred at 20 to 30 C for 2 hours.Followed by the addition of hydrochloric acid solution (1 M, 800 mL) and aqueous sodium thiosulfate solution (10% by mass) as the percentage of sodium thiosulfate and the total mass of sodium thiosulfate aqueous solution, 400 mL. ,The aqueous phase was extracted with 1 L of dichloromethane,The organic phase was washed twice with saturated brine,Dried over anhydrous sodium sulfate,filter,Concentration under reduced pressure gave hexanoic acid derivative IV (254.6 g, 99.5%),Yield 99.5%Purity: 95.6% (GC)., 63095-51-2
As the paragraph descriping shows that 63095-51-2 is playing an increasingly important role.
Reference£º
Patent; Shanghai Bocimed Pharmaceutical Co., Ltd.; Ying, Shuhuan; Pi, Hongjun; Chen, Jian; Zhou, Wei; Zhang, Jueming; (13 pag.)CN106588740; (2017); A;,
Tetrahydrofuran – Wikipedia
Tetrahydrofuran | (CH2)3CH2O – PubChem