New learning discoveries about 144870-96-2

144870-96-2 4-Aminotetrahydrofuran-3-ol 10486809, aTetrahydrofurans compound, is more and more widely used in various.

144870-96-2, 4-Aminotetrahydrofuran-3-ol is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated

To a solution of 4-aminotetrahydrofuran-3-ol (74.5 mg, 0.722 mmol) and ethyl 4-(chlorosulfonyl)-3-fluoro-l-methyl-lH-pyrrole-2-carboxylate (150 mg, 0.556 mmol) in dry acetonitrile (4 mL), dry DIPEA (0.3 mL, 1.7223 mmol) was added at rt. After lh mixture was evaporated under reduced pressure to afford a yellow solid (325 mg). Crude was purified by flash chromatography (Petroleum ether/ AcOEt) to afford D44 as a light yellow solid (178 mg, y= 95%). Method 1 : Rt=l.28 min, m/z=337 (M+H)+. The compound is the trans racemic mixture at the tetrahydrofuranyl ring., 144870-96-2

144870-96-2 4-Aminotetrahydrofuran-3-ol 10486809, aTetrahydrofurans compound, is more and more widely used in various.

Reference£º
Patent; OSPEDALE SAN RAFFAELE S.R.L.; IRBM S.P.A.; PROMIDIS S.R.L.; ISTITUTO NAZIONALE DI GENETICA MOLECOLARE – INGM; DE FRANCESCO, Raffaele; DONNICI, Lorena; GUIDOTTI, Luca; IANNACONE, Matteo; DI FABIO, Romano; SUMMA, Vincenzo; PRANDI, Adolfo; RANDAZZO, Pietro; GORNATI, Davide; GRILLO, Alessandro; FERRANTE, Luca; BENCHEVA, Leda Ivanova; DE MATTEO, Marilenia; FERRARA, Marco; (238 pag.)WO2020/30781; (2020); A1;,
Tetrahydrofuran – Wikipedia
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