With the rapid development and complex challenges of chemical substances, new drug synthesis pathways are usually the most effective.5061-21-2,2-Bromo-4-butanolide,as a common compound, the synthetic route is as follows.,5061-21-2
EXAMPLE VI 2-Azido-gamma-butyrolactone 1.56 g (10 mmol) of 2-bromo-gamma-butyrolactone are dissolved in 2 ml of dimethylformamide and treated at 0 C. with 612 mg (12.5 mmol) of lithium azide. The mixture is stirred at room temperature for 2 h, treated with water and extracted three times with methylene chloride. The combined organic phases are washed three times with water, dried over sodium sulphate and concentrated. 1.10 g (86.6% of theory) of the title compound are obtained. MS: 127
The synthetic route of 5061-21-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; Bayer Aktiengesellschaft; US6194428; (2001); B1;,
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