138498-97-2, 2-(Tetrahydrofuran-3-yl)acetic acid is a Tetrahydrofurans compound, ?involved in a variety of chemical synthesis. Rlated chemical reaction is continuously updated
To a mixture of A-2 (100.00 mg, 691.75 mmol), PYBOP (539.97 mg, 1.04 mmol) in DCM (10.00 mL) was added 2-tetrahydrofuran-3-ylacetic acid (90.02 mg, 691.75 mmol) and DIPEA (362.44 _, 2.08 mmol), and the mixture was stirred at 25 C for 1 hour. The mixture was concentrated to give crude A-11 (800.00 mg), which was used directly without any further purification. LCMS Rt = 0.18 min using Method B, MS ESI calcd. For C10H14CIN4O2 [M+H]+ 257.1, found 257.0.
The synthetic route of 138498-97-2 has been constantly updated, and we look forward to future research findings.
Reference£º
Patent; PRAXIS PRECISION MEDICINES, INC.; REDDY, Kiran; MARTINEZ BOTELLA, Gabriel; GRIFFIN, Andrew, Mark; MARRON, Brian, Edward; (364 pag.)WO2018/98499; (2018); A1;,
Tetrahydrofuran – Wikipedia
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